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ISL1 抗体

This anti-ISL1 antibody is a 小鼠 单克隆 antibody detecting ISL1 in ELISA, IHC 和 ICC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN969219
发货至: 中国

Quick Overview for ISL1 抗体 (ABIN969219)

抗原

See all ISL1 抗体
ISL1 (ISL LIM Homeobox 1 (ISL1))

适用

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宿主

  • 80
  • 10
小鼠

克隆类型

  • 65
  • 25
单克隆

标记

  • 47
  • 6
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  • 2
  • 2
  • 2
  • 2
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  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This ISL1 antibody is un-conjugated

应用范围

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  • 1
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ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

1H9
  • 原理

    ISL1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human ISL1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Elshatory, Gan: "The LIM-homeobox gene Islet-1 is required for the development of restricted forebrain cholinergic neurons." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 28, Issue 13, pp. 3291-7, (2008) (PubMed).

  • 抗原

    ISL1 (ISL LIM Homeobox 1 (ISL1))

    别名

    ISL1

    背景

    ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.

    分子量

    39 kDa

    UniProt

    P61371

    途径

    Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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