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ICAM1 抗体 (AA 28-480)

This anti-ICAM1 antibody is a 小鼠 单克隆 antibody detecting ICAM1 in ELISA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN969206
发货至: 中国

Quick Overview for ICAM1 抗体 (AA 28-480) (ABIN969206)

抗原

See all ICAM1 抗体
ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ICAM1 antibody is un-conjugated

应用范围

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ELISA

克隆位点

6G12
  • 抗原表位

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    AA 28-480

    原理

    ICAM1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yang, Cullen, Li, Chapman, Jewell: "Susceptibility to primary sclerosing cholangitis is associated with polymorphisms of intercellular adhesion molecule-1." in: Journal of hepatology, Vol. 40, Issue 3, pp. 375-9, (2004) (PubMed).

  • 抗原

    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

    别名

    ICAM1

    背景

    ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.

    分子量

    57.8 kDa

    基因ID

    3383

    UniProt

    P05362

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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