ICAM1 抗体
(7 references)-
- 抗原 See all ICAM1 抗体
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
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适用
- 人, 大鼠, Cow
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ICAM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 特异性
- The antibody MEM-111 reacts with an extracellular epitope of CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation, it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells.
- 交叉反应 （详细）
- Rat, Human, Bovine
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Raji human Burkitt's lymphoma cell line
- 克隆位点
- MEM-111
- 亚型
- IgG2a
- Top Product
- Discover our top product ICAM1 Primary Antibody
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anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 201-300) antibody
ICAM1 适用: 人, 小鼠, 大鼠, 兔 WB, FACS, ELISA, IHC (p), IHC (fro), ICC, IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 198-537) antibodyICAM1 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 102-306) antibodyICAM1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibodyICAM1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (pTyr512) antibodyICAM1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 41-464) antibodyICAM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 27-209) antibodyICAM1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 1-532) antibodyICAM1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3H8-2G6 unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 313-327) antibodyVerified ICAM1 适用: 人 WB, FACS, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Intercellular Adhesion Molecule 1 (ICAM1) (AA 250-480) antibodyICAM1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Flow cytometry: Recommended dilution: 0.5-4 μg/mL.
Immunohistochemistry (paraffin sections): Recommended dilution: 10 μg/mL, positive tissue: thymus, RE cells.
Western blotting: Positive control: RAJI cell line K562 leukemia cell line, JY cell line, aa ctivated T-lymphocytes, non-reducing conditions. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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: "LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8128-36, (2007) (PubMed).
: "Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow." in: American journal of physiology. Cell physiology, Vol. 284, Issue 4, pp. C977-87, (2003) (PubMed).
: "Susceptibility of immature and mature Langerhans cell-type dendritic cells to infection and immunomodulation by human cytomegalovirus." in: Journal of virology, Vol. 77, Issue 13, pp. 7563-74, (2003) (PubMed).
: "Eotaxin-2 alters eosinophil integrin function via mitogen-activated protein kinases." in: American journal of respiratory cell and molecular biology, Vol. 26, Issue 6, pp. 645-9, (2002) (PubMed).
: "Molecular mechanisms of improved adhesion and growth of an endothelial cell line cultured on polystyrene implanted with fluorine ions." in: Biomaterials, Vol. 21, Issue 11, pp. 1173-9, (2000) (PubMed).
: "A variety of cytokines and immunologically relevant surface molecules are expressed by normal human skeletal muscle cells under proinflammatory stimuli." in: Clinical and experimental immunology, Vol. 113, Issue 3, pp. 407-14, (1998) (PubMed).
: "E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro." in: Immunology, Vol. 77, Issue 4, pp. 543-9, (1993) (PubMed).
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: "LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8128-36, (2007) (PubMed).
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- 抗原
- ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
- 别名
- CD54 (ICAM1 产品)
- 别名
- BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
- 物质类
- Viral Protein
- 背景
- Intercellular adhesion molecule 1,CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.,ICAM-1, BB2, P3.58
- 基因ID
- 3383
- UniProt
- P05362
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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