电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Hexokinase 1 抗体

This anti-Hexokinase 1 antibody is a 小鼠 单克隆 antibody detecting Hexokinase 1 in WB, IHC, ELISA 和 ICC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969194
发货至: 中国

Quick Overview for Hexokinase 1 抗体 (ABIN969194)

抗原

See all Hexokinase 1 (HK1) 抗体
Hexokinase 1 (HK1)

适用

  • 101
  • 61
  • 42
  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 117
  • 16
小鼠

克隆类型

  • 108
  • 25
单克隆

标记

  • 81
  • 20
  • 8
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This Hexokinase 1 antibody is un-conjugated

应用范围

  • 108
  • 68
  • 42
  • 35
  • 31
  • 21
  • 15
  • 12
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

克隆位点

7A7
  • 原理

    HK1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human HK1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Martins-de-Souza, Gattaz, Schmitt, Rewerts, Marangoni, Novello, Maccarrone, Turck, Dias-Neto: "Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis." in: Journal of neural transmission (Vienna, Austria : 1996), Vol. 116, Issue 3, pp. 275-89, (2009) (PubMed).

    Tsai: "Function of interdomain alpha-helix in human brain hexokinase: covalent linkage and catalytic regulation between N- and C-terminal halves." in: Journal of biomedical science, Vol. 14, Issue 2, pp. 195-202, (2007) (PubMed).

    Stelzl, Worm, Lalowski, Haenig, Brembeck, Goehler, Stroedicke, Zenkner, Schoenherr, Koeppen, Timm, Mintzlaff, Abraham, Bock, Kietzmann, Goedde, Toksöz, Droege, Krobitsch, Korn, Birchmeier, Lehrach et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, (2005) (PubMed).

  • 抗原

    Hexokinase 1 (HK1)

    别名

    HK1

    背景

    The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose- 6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines.

    分子量

    102 kDa

    UniProt

    P19367

    途径

    Carbohydrate Homeostasis, Warburg Effect
You are here:
Chat with us!