GFI1 抗体
(2 references)Quick Overview for GFI1 抗体 (ABIN969174)
抗原
See all GFI1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- GFI1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human GFI1 expressed in E. Coli.
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亚型
- IgG1
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anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibody
GFI1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Growth Factor Independent 1 (GFI1) antibodyGFI1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-91) antibodyGFI1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 280-330) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 1-422) antibodyGFI1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (AA 32-81) antibodyGFI1 适用: 人, 大鼠, Cow, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Independent 1 (GFI1) (N-Term) antibodyGFI1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 103, Issue 3-5, pp. 742-6, (2007) (PubMed).
: "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. ..." in: Genome research, Vol. 16, Issue 1, pp. 55-65, (2006) (PubMed).
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: "Role of oncoprotein growth factor independent-1 (GFI1) in repression of 25-hydroxyvitamin D 1alpha-hydroxylase (CYP27B1): a comparative analysis in human prostate cancer and kidney cells." in: The Journal of steroid biochemistry and molecular biology, Vol. 103, Issue 3-5, pp. 742-6, (2007) (PubMed).
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- GFI1 (Growth Factor Independent 1 (GFI1))
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别名
- GFI1
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背景
- This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.Expression of GFl1 ranges from the hematopoietic and lymphoid system, to sensory epithelia, lung and parts of the CNS.
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分子量
- 45 kDa
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基因ID
- 2672
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UniProt
- Q99684
抗原
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