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Glucagon 抗体

This anti-Glucagon antibody is a 小鼠 单克隆 antibody detecting Glucagon in ELISA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN969171
发货至: 中国

Quick Overview for Glucagon 抗体 (ABIN969171)

抗原

See all Glucagon (GCG) 抗体
Glucagon (GCG)

适用

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宿主

  • 101
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小鼠

克隆类型

  • 100
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单克隆

标记

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This Glucagon antibody is un-conjugated

应用范围

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ELISA

克隆位点

2F9
  • 原理

    GCG Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human GCG expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Arnés, González, Tornero-Esteban, Sancho, Acitores, Valverde, Delgado, Villanueva-Peñacarrillo: "Characteristics of GLP-1 and exendins action upon glucose transport and metabolism in type 2 diabetic rat skeletal muscle." in: International journal of molecular medicine, Vol. 22, Issue 1, pp. 127-32, (2008) (PubMed).

  • 抗原

    Glucagon (GCG)

    别名

    GCG

    背景

    The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.Tissue specificity: Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.

    分子量

    21 kDa

    基因ID

    2641

    UniProt

    P01275

    途径

    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
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