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Glucagon 抗体 (N-Term)

Name: Glucagon 抗体 (N-Term)
SKU: ABIN3042419
Availability: OutOfStock

GCG 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti- GLP1 Picoband antibody, IHC(P) IHC(P): Rat Pancreas Tissue (Glucagon 抗体 (N-Term))

IHC

Anti- GLP1 Picoband antibody, IHC(P) IHC(P): Human Pancreatic Cancer Tissue (Glucagon 抗体 (N-Term))

IHC

Anti- GLP1 Picoband antibody, IHC(P) IHC(P): Mouse Pancreas Tissue (Glucagon 抗体 (N-Term))

IHC

3 images

(6 references)

产品编号 ABIN3042419

发货至: 中国

Datasheet as PDF

抗原 See all Glucagon (GCG) 抗体

Glucagon (GCG)
抗原表位
15

13

11

7

6

6

4

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1
AA 53-81, N-Term
适用
116

45

40

12

5

5

4

3

3

3

3

2

2

1

1

1
人, 大鼠, 小鼠
宿主
74

30

14

4

1
兔
Compatible Secondaries
克隆类型
81

41
多克隆
标记
74

10

6

5

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This Glucagon antibody is un-conjugated
应用范围
52

50

28

16

13

13

13

12

12

11

10

9

3

3

2

2

2

2

2

1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Glucagon(GCG) detection. Tested with IHC-P in Human,Mouse,Rat.

序列

HSQGTFTSDY SKYLDSRRAQ DFVQWLMNT

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Glucagon(GCG) detection. Tested with IHC-P in Human,Mouse,Rat.
Gene Name: glucagon
Protein Name: Glucagon

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human GLP1 (53-81aa HSQGTFTSDYSKYLDSRRAQDFVQWLMNT), identical to the related mouse and rat sequences.

亚型

IgG

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anti-Glucagon (GCG) (AA 1-180) antibody
GCG 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1E2-E6 unconjugated

anti-Glucagon (GCG) antibody
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anti-Glucagon (GCG) (AA 53-81) antibody
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anti-Glucagon (GCG) (AA 23-180) antibody
GCG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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anti-Glucagon (GCG) (AA 25-54) antibody
GCG 适用: 人, 小鼠 WB, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Glucagon (GCG) (AA 1-180) antibody
GCG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Yang, Yan, Tong, Zhang, Chen, Xue, Wang, Chu, Jin, Li: "Chronic oscillating glucose challenges disarrange innate immune homeostasis to potentiate the variation of neutrophil-lymphocyte ratio in rats with or without hidden diabetes mellitus." in: Diabetes, metabolic syndrome and obesity : targets and therapy, Vol. 11, pp. 277-288, (2018) (PubMed).

Wang, Tian, Chen, Tan, Xie, Chen, Fu, Chen, Xu, Wei: "Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in db/db mice." in: Scientific reports, Vol. 7, Issue 1, pp. 14707, (2017) (PubMed).

Zhang, Ye, Wang, Gao, Tan, Zhuo, Liu, Xia, Yang, Li: "Kidney-targeted transplantation of mesenchymal stem cells by ultrasound-targeted microbubble destruction promotes kidney repair in diabetic nephropathy rats." in: BioMed research international, Vol. 2013, pp. 526367, (2013) (PubMed).

Tang, Zhu, Fan, Zhang, Li, Liu, Chen, Zhang, Zhou, Wei: "Intra-arterial targeted islet-specific expression of Sirt1 protects ? cells from streptozotocin-induced apoptosis in mice." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 19, Issue 1, pp. 60-6, (2011) (PubMed).

Lan, Yue, Han, Shi, Yang, Pu, Yao, Kang: "Genome-wide identification of TCF7L2/TCF4 target miRNAs reveals a role for miR-21 in Wnt-driven epithelial cancer." in: International journal of oncology, Vol. 40, Issue 2, pp. 519-26, (2011) (PubMed).

Chen, Yang, Zheng, Hu, Kong, Zhang: "Effect of catch-up growth after food restriction on the entero-insular axis in rats." in: Nutrition & metabolism, Vol. 7, pp. 45, (2010) (PubMed).
抗原

Glucagon (GCG)

别名

GCG (GCG 产品)

别名

GLP1 antibody, GLP2 antibody, GRPP antibody, GLP-1 antibody, Glu antibody, PPG antibody, GCG antibody, gcg-A antibody, gcg1 antibody, glucagon antibody, glucagon L homeolog antibody, GCG antibody, Gcg antibody, gcg.L antibody

背景

GCG is also known as GLP1, or Glucagon. Glucagon is a 29-amino acid pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. It is mapped to 2q36-2q37. GLP1, also known as 7-37 for the codons of the preproglucagon molecule which encode it, renders pancreatic beta-cells 'glucose-competent' and may be useful in the treatment of noninsulin-dependent diabetes mellitus. Also, GLP1 is a potent insulin secretagogue. It plays a major role in the enteroinsular axis, accounting, for example, for the finding that plasma insulin levels accompanying oral intake of glucose are greater than those observed when glucose is given intravenously.

Synonyms: GCG antibody|glicentin-related polypeptide antibody|GLP-1 antibody|GLP-1(7-36) antibody|GLP-1(7-37) antibody|GLP-2 antibody|GLP1 antibody|GLP1, included antibody|GLP2 antibody|GLP2, included antibody|GLUC_HUMAN antibody|Glucagon antibody|Glucagon like peptide 1 antibody|glucagon-like peptide 1 antibody|Glucagon-like peptide 1, included antibody|Glucagon-like peptide 2 antibody|Glucagon-like peptide 2, included antibody|GRPP antibody|OXM antibody|OXY antibody|preproglucagon antibody

基因ID

2641

UniProt

P01275

途径

Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling