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GATA4 抗体

Name: GATA4 抗体
Brand: antibodies-online
SKU: ABIN969169
Availability: OutOfStock

This anti-GATA4 antibody is a 小鼠单克隆 antibody detecting GATA4 in WB 和 ELISA. Suitable for 人和大鼠. This Primary Antibody has been cited in 2+ publications.

Western blot analysis using GATA4 mouse mAb against rat fetal heart (1) and adult heart (2) tissues lysate. (GATA4 抗体)

1 image

(2 references)

产品编号 ABIN969169

发货至: 中国

Quick Overview for GATA4 抗体 (ABIN969169)

抗原

See all GATA4 抗体

GATA4 (GATA Binding Protein 4 (GATA4))

适用

人, 大鼠

宿主

小鼠

克隆类型

单克隆

标记

This GATA4 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

克隆位点

6H10

Discover our top product GATA4 Primary Antibody

原理

GATA4 Antibody

纯化方法

Ascitic fluid

免疫原

Purified recombinant fragment of human GATA4 expressed in E. Coli.

亚型

IgG2b
anti-GATA Binding Protein 4 (GATA4) (pSer105) antibody
GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (pSer262) antibody
GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) antibody
GATA4 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 228-440) antibody
GATA4 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 50-150) antibody
GATA4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 261-360) antibody
GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 201-442) antibody
GATA4 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 330-380) antibody
GATA4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 343-442) antibody
GATA4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C6 unconjugated

anti-GATA Binding Protein 4 (GATA4) (AA 296-442) antibody
GATA4 适用: 人 WB, IF 宿主: 小鼠 Monoclonal 1H8 unconjugated

应用备注

ELISA: 1/10000

限制

仅限研究用
状态

Liquid

缓冲液

Ascitic fluid containing 0.03 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rajagopal, Ma, Obler, Shen, Manichaikul, Tomita-Mitchell, Boardman, Briggs, Garg, Srivastava, Goldmuntz, Broman, Benson, Smoot, Pu: "Spectrum of heart disease associated with murine and human GATA4 mutation." in: Journal of molecular and cellular cardiology, Vol. 43, Issue 6, pp. 677-85, (2007) (PubMed).

Belaguli, Sepulveda, Nigam, Charron, Nemer, Schwartz: "Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators." in: Molecular and cellular biology, Vol. 20, Issue 20, pp. 7550-8, (2000) (PubMed).
抗原

GATA4 (GATA Binding Protein 4 (GATA4))

别名

GATA4

背景

GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of zinc-finger transcription factors. Members of this family is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. These factors recognize the GATA motif which is present in the promoters of many genes. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.

分子量

46 kDa

基因ID

2626

UniProt

P43694

途径

Peptide Hormone Metabolism, Carbohydrate Homeostasis