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GATA4 抗体 (pSer105)

GATA4 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6256094
发货至: 中国
  • 抗原 See all GATA4 抗体
    GATA4 (GATA Binding Protein 4 (GATA4))
    抗原表位
    • 15
    • 12
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer105
    适用
    • 85
    • 63
    • 63
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 79
    • 7
    克隆类型
    • 70
    • 16
    多克隆
    标记
    • 51
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GATA4 antibody is un-conjugated
    应用范围
    • 62
    • 28
    • 19
    • 17
    • 13
    • 13
    • 11
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Phospho-GATA4 (Ser105) Antibody detects endogenous levels of GATA4 only when phosphorylated at Serine 105.
    预测反应
    Pig,Bovine,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human GATA4 around the phosphorylation site of Ser105.
    亚型
    IgG
    Top Product
    Discover our top product GATA4 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    GATA4 (GATA Binding Protein 4 (GATA4))
    别名
    GATA4 (GATA4 产品)
    别名
    gata-4 antibody, xgata4 antibody, xGATA-4 antibody, MGC81427 antibody, GATA4 antibody, GATA-4 antibody, Gata4 antibody, gata4 antibody, ASD2 antibody, VSD1 antibody, Gata-4 antibody, gata antibody, GATA binding protein 4 antibody, GATA binding protein 4 L homeolog antibody, glutamyl-tRNA(Gln) amidotransferase subunit A antibody, gata4 transcription factor antibody, GATA binding protein 4 S homeolog antibody, GATA4 antibody, gata4.L antibody, gata4 antibody, gatA4 antibody, Gata4 antibody, gata4.S antibody
    背景

    Description: Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function (PubMed:24000169, PubMed:27984724). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (PubMed:27984724). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement (PubMed:20081228). Required during testicular development (PubMed:21220346). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase (PubMed:15734735).

    Gene: GATA4

    分子量
    44kDa
    基因ID
    2626
    UniProt
    P43694
    途径
    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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