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c-FOS 抗体

This anti-c-FOS antibody is a 小鼠 单克隆 antibody detecting c-FOS in WB, ELISA, IHC 和 FACS. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969150
发货至: 中国

Quick Overview for c-FOS 抗体 (ABIN969150)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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宿主

  • 187
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小鼠

克隆类型

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单克隆

标记

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This c-FOS antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

克隆位点

2G2
  • 原理

    FOS Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human FOS expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Das, Muniyappa: "c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1." in: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 53-63, (2010) (PubMed).

    Wang, Sun, Jiang, Zhang, Wolfl: "FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis." in: Cancer investigation, Vol. 27, Issue 8, pp. 816-24, (2009) (PubMed).

  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    FOS

    背景

    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

    分子量

    40.7 kDa

    基因ID

    2353

    UniProt

    P01100

    途径

    S100 Proteins
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