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FGF2 抗体

This anti-FGF2 antibody is a 小鼠 单克隆 antibody detecting FGF2 in ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969137
发货至: 中国

Quick Overview for FGF2 抗体 (ABIN969137)

抗原

See all FGF2 抗体
FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FGF2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)

克隆位点

2H5G2C11
  • 原理

    FGF2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of FGF2 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Kim, Shin, Choi, Kim, Ahn, Lee, Park, Kim, Mok, Nam: "A preliminary results of a randomized trial comparing monthly 5-flourouracil and cisplatin to weekly cisplatin alone combined with concurrent radiotherapy for locally advanced cervical cancer." in: Cancer research and treatment : official journal of Korean Cancer Association, Vol. 37, Issue 1, pp. 37-43, (2009) (PubMed).

    Romanov, James, Sherrington, Pettitt: "Basic fibroblast growth factor suppresses p53 activation in the neoplastic cells of a proportion of patients with chronic lymphocytic leukaemia." in: Oncogene, Vol. 24, Issue 45, pp. 6855-60, (2005) (PubMed).

    Webber, Chen, Hehr, Johnston, McFarlane: "Multiple signaling pathways regulate FGF-2-induced retinal ganglion cell neurite extension and growth cone guidance." in: Molecular and cellular neurosciences, Vol. 30, Issue 1, pp. 37-47, (2005) (PubMed).

  • 抗原

    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

    别名

    FGF2

    背景

    FGF2 is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of anguogenesis. Due to its basic pH , the factor is named FGF-2 (basic FGF, bFGF).Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FIBROBLAST GROWTH FACTOR 1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor (FIBROBLAST GROWTH FACTOR 1).

    基因ID

    2247

    UniProt

    P09038

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
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