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Fibulin 5 抗体 (AA 242-448)

Cited in 3+ publications. This 小鼠 单克隆 anti-Fibulin 5 antibody (Clone 1G6A4) specifically detects Fibulin 5 in IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN969131
发货至: 中国
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Quick Overview for Fibulin 5 抗体 (AA 242-448) (ABIN969131)

抗原

See all Fibulin 5 (FBLN5) 抗体
Fibulin 5 (FBLN5)

适用

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宿主

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小鼠

克隆类型

  • 61
  • 13
单克隆

标记

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This Fibulin 5 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA

克隆位点

1G6A4
  • 抗原表位

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    AA 242-448

    原理

    FBLN5 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wang, LeMaire, Chen, Carter, Shen, Gan, Bartsch, Wilks, Utama, Ou, Thompson, Coselli, Wang: "Decreased expression of fibulin-5 correlates with reduced elastin in thoracic aortic dissection." in: Surgery, Vol. 138, Issue 2, pp. 352-9, (2005) (PubMed).

    Stone, Braun, Russell, Kuehn, Lotery, Moore, Eastman, Casavant, Sheffield: "Missense variations in the fibulin 5 gene and age-related macular degeneration." in: The New England journal of medicine, Vol. 351, Issue 4, pp. 346-53, (2004) (PubMed).

    Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: "Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene." in: American journal of human genetics, Vol. 72, Issue 4, pp. 998-1004, (2003) (PubMed).

  • 抗原

    Fibulin 5 (FBLN5)

    别名

    FBLN5

    背景

    FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

    UniProt

    Q9UBX5

    途径

    SARS-CoV-2 Protein Interactome
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