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FABP4 抗体

This anti-FABP4 antibody is a 小鼠 单克隆 antibody detecting FABP4 in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969126
发货至: 中国

Quick Overview for FABP4 抗体 (ABIN969126)

抗原

See all FABP4 抗体
FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

适用

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宿主

  • 144
  • 31
  • 4
  • 2
  • 1
小鼠

克隆类型

  • 132
  • 50
单克隆

标记

  • 102
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  • 1
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This FABP4 antibody is un-conjugated

应用范围

  • 122
  • 68
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  • 27
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  • 15
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  • 8
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ELISA

克隆位点

9B8D
  • 原理

    FABP4 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of FABP4 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Tuncman, Erbay, Hom, De Vivo, Campos, Rimm, Hotamisligil: "A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 18, pp. 6970-5, (2006) (PubMed).

    Gericke, Smith, Moore, Mendelsohn, Storch: "Adipocyte fatty acid-binding protein: interaction with phospholipid membranes and thermal stability studied by FTIR spectroscopy." in: Biochemistry, Vol. 36, Issue 27, pp. 8311-7, (1997) (PubMed).

  • 抗原

    FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

    别名

    FABP4

    背景

    Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.

    分子量

    14 kDa

    基因ID

    2167

    UniProt

    P15090

    途径

    Brown Fat Cell Differentiation
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