ETV4 抗体 (AA 50-109)
(3 references)Quick Overview for ETV4 抗体 (AA 50-109) (ABIN969121)
抗原
See all ETV4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 50-109
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原理
- ETV4 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human ETV4 (aa50-109) expressed in E. Coli.
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亚型
- IgG1
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anti-Ets Variant 4 (ETV4) (AA 1-207) antibody
ETV4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (AA 1-207) antibodyETV4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G9-1B9 unconjugated
anti-Ets Variant 4 (ETV4) (AA 419-447), (C-Term) antibodyETV4 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20008 unconjugated
anti-Ets Variant 4 (ETV4) (AA 181-230) antibodyETV4 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) antibodyETV4 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (Middle Region) antibodyETV4 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) antibodyETV4 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (AA 426-455), (C-Term) antibodyETV4 适用: 人, 小鼠 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) antibodyETV4 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (AA 79-178) antibodyETV4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1." in: Molecular carcinogenesis, Vol. 45, Issue 9, pp. 667-75, (2006) (PubMed).
: "PEA3 cooperates with c-Jun in regulation of HER2/neu transcription." in: Oncology reports, Vol. 16, Issue 1, pp. 153-8, (2006) (PubMed).
: "Elevated beta1,4-galactosyltransferase I in highly metastatic human lung cancer cells. Identification of E1AF as important transcription activator." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12503-16, (2005) (PubMed).
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: "Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1." in: Molecular carcinogenesis, Vol. 45, Issue 9, pp. 667-75, (2006) (PubMed).
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- ETV4 (Ets Variant 4 (ETV4))
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别名
- ETV4
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背景
- ETV4: ets variant gene 4 (E1A enhancer binding protein, E1AF), also known as PEA3. Several members of the Ets gene family are known to encode sequencespecific DNA binding proteins. These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-a. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.
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分子量
- 54 kDa
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基因ID
- 2118
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UniProt
- P43268
抗原
-
