ETV4 抗体 (Middle Region)
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北京 101111
Quick Overview for ETV4 抗体 (Middle Region) (ABIN2779533)
抗原
See all ETV4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- ETV4 Antibody - middle region
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序列
- HSSVFQQPLD ICHSFTSQGG GREPLPAPYQ HQLSEPCPPY PQQSFKQEYH
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预测反应
- Cow: 100%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against ETV4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ETV4
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anti-Ets Variant 4 (ETV4) (AA 1-207) antibody
ETV4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (AA 419-447), (C-Term) antibodyETV4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20008 unconjugated
anti-Ets Variant 4 (ETV4) (AA 1-207) antibodyETV4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G9-1B9 unconjugated
anti-Ets Variant 4 (ETV4) (AA 50-109) antibodyETV4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1A2G3 unconjugated
anti-Ets Variant 4 (ETV4) (AA 181-230) antibodyETV4 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) antibodyETV4 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) antibodyETV4 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ets Variant 4 (ETV4) (Center) antibodyETV4 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099878
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "An Interaction with Ewing's Sarcoma Breakpoint Protein EWS Defines a Specific Oncogenic Mechanism of ETS Factors Rearranged in Prostate Cancer." in: Cell reports, Vol. 17, Issue 5, pp. 1289-1301, (2016) (PubMed).
: "Inactivation of Capicua drives cancer metastasis." in: Nature genetics, Vol. 49, Issue 1, pp. 87-96, (2016) (PubMed).
: "Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation." in: Molecular cancer, Vol. 13, pp. 61, (2014) (PubMed).
: "The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells." in: Genes & cancer, Vol. 1, Issue 10, pp. 1044-1052, (2011) (PubMed).
: "Oncogenic ETS proteins mimic activated RAS/MAPK signaling in prostate cells." in: Genes & development, Vol. 25, Issue 20, pp. 2147-57, (2011) (PubMed).
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- ETV4 (Ets Variant 4 (ETV4))
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别名
- ETV4
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背景
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Background Information: The protein encoded by the ETV4 gene is known to play a role in ovarian and breast malignancies as well as in the early stage of colorectal carcinogenesis.
Gene Name: Ets variant 4
Alternative Symbols: E1AF, PEA3, E1A-F, PEAS3
Protein Name: ETS translocation variant 4
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分子量
- 54kDa
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基因ID
- 2118
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NCBI登录号
- NP_001977
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UniProt
- P43268
抗原
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