Estrogen Receptor alpha 抗体
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- 抗原 See all Estrogen Receptor alpha (ESR1) 抗体
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Estrogen Receptor alpha antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- ESR1 Antibody
- 序列
- SLQKYYITGE AEGFPATVc
- 纯化方法
- Ascitic fluid
- 免疫原
- Synthetic peptide corresponding to aa(SLQKYYITGEAEGFPATVc) of human ESR1, conjugated to KLH.
- 克隆位点
- 2G112B3
- 亚型
- IgG1
- Top Product
- Discover our top product ESR1 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Relationship of volumetric bone mineral density and structural parameters with ERalpha gene polymorphisms." in: Calcified tissue international, Vol. 80, Issue 5, pp. 307-15, (2007) (PubMed).
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Relationship of volumetric bone mineral density and structural parameters with ERalpha gene polymorphisms." in: Calcified tissue international, Vol. 80, Issue 5, pp. 307-15, (2007) (PubMed).
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- 抗原
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- 别名
- ESR1 (ESR1 产品)
- 背景
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Description: ESR1: estrogen receptor 1. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Aliases: ER, ESR, Era, ESRA, NR3A1
- 基因ID
- 2099
- HGNC
- 2099
- UniProt
- P03372
- 途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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