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DKK1 抗体

This anti-DKK1 antibody is a 小鼠 单克隆 antibody detecting DKK1 in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969085
发货至: 中国

Quick Overview for DKK1 抗体 (ABIN969085)

抗原

See all DKK1 抗体
DKK1 (Dickkopf Homolog 1 (DKK1))

适用

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宿主

  • 118
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小鼠

克隆类型

  • 109
  • 40
单克隆

标记

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This DKK1 antibody is un-conjugated

应用范围

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ELISA

克隆位点

2H2
  • 原理

    DKK1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of DKK1 expressed in E. Coli.

    亚型

    IgG2b
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yamamoto, Sakane, Yamamoto, Michiue, Kikuchi: "Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling." in: Developmental cell, Vol. 15, Issue 1, pp. 37-48, (2008) (PubMed).

    Qiao, Xu, Zhao, Ye, Zhang: "Dkk-1 secreted by mesenchymal stem cells inhibits growth of breast cancer cells via depression of Wnt signalling." in: Cancer letters, Vol. 269, Issue 1, pp. 67-77, (2008) (PubMed).

  • 抗原

    DKK1 (Dickkopf Homolog 1 (DKK1))

    别名

    DKK1

    背景

    DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

    分子量

    28.7 kDa

    基因ID

    22943

    UniProt

    O94907

    途径

    WNT signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation
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