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CST3 抗体

This anti-CST3 antibody is a 小鼠 单克隆 antibody detecting CST3 in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969070
发货至: 中国

Quick Overview for CST3 抗体 (ABIN969070)

抗原

See all CST3 抗体
CST3 (Cystatin C (CST3))

适用

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  • 37
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  • 1
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宿主

  • 84
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  • 10
  • 3
  • 2
  • 1
小鼠

克隆类型

  • 95
  • 49
单克隆

标记

  • 72
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  • 5
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  • 3
  • 2
  • 2
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  • 2
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CST3 antibody is un-conjugated

应用范围

  • 90
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Western Blotting (WB), ELISA

克隆位点

5H2
  • 原理

    CST3 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CST3 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Helisalmi, Väkevä, Hiltunen, Soininen: "Flanking markers of cystatin c (CST3) gene do not show association with Alzheimer's disease." in: Dementia and geriatric cognitive disorders, Vol. 27, Issue 4, pp. 318-21, (2009) (PubMed).

    Rehman, Fought, Solomon: "N-acetylcysteine effect on serum creatinine and cystatin C levels in CKD patients." in: Clinical journal of the American Society of Nephrology : CJASN, Vol. 3, Issue 6, pp. 1610-4, (2008) (PubMed).

  • 抗原

    CST3 (Cystatin C (CST3))

    别名

    CST3

    背景

    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. (provided by RefSeq)Tissue specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.

    分子量

    42 kDa

    基因ID

    1471

    UniProt

    P01034
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