CRTC3 抗体
(2 references)-
- 抗原 See all CRTC3 抗体
- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CRTC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
- 原理
- CRTC3 Antibody
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human CRTC3 expressed in E. Coli.
- 克隆位点
- 5G9
- 亚型
- IgG1
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anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 373-480) antibody
CRTC3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 176-274) antibodyCRTC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (Internal Region) antibodyCRTC3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 1-260) antibodyCRTC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 1-103) antibodyCRTC3 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).
: "A new type of MAML2 fusion in mucoepidermoid carcinoma." in: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).
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: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).
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- 抗原
- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
- 别名
- CRTC3 (CRTC3 产品)
- 背景
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Description: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
Aliases: TORC3, FLJ21868, CRTC3
- 分子量
- 68kDa
- 基因ID
- 64784
- HGNC
- 64784
- UniProt
- Q6UUV7
- 途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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