电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CRTC3 抗体

CRTC3 适用: 人, 猴 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated
产品编号 ABIN969068
发货至: 中国
  • 抗原 See all CRTC3 抗体
    CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
    适用
    • 32
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 猴
    宿主
    • 30
    • 2
    小鼠
    克隆类型
    • 26
    • 6
    单克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRTC3 antibody is un-conjugated
    应用范围
    • 25
    • 12
    • 12
    • 12
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    原理
    CRTC3 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CRTC3 expressed in E. Coli.
    克隆位点
    5G9
    亚型
    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Nakayama, Miyabe, Okabe, Sakuma, Ijichi, Hasegawa, Nagatsuka, Shimozato, Inagaki: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).

    Fehr, Röser, Heidorn, Hallas, Löning, Bullerdiek: "A new type of MAML2 fusion in mucoepidermoid carcinoma." in: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).

  • 抗原
    CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
    别名
    CRTC3 (CRTC3 产品)
    背景
    Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
    分子量
    68 kDa
    基因ID
    64784
    UniProt
    Q6UUV7
    途径
    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
You are here:
Chat with us!