CRTC3 抗体
(2 references)Quick Overview for CRTC3 抗体 (ABIN969068)
抗原
See all CRTC3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CRTC3 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human CRTC3 expressed in E. Coli.
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亚型
- IgG1
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anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 373-480) antibody
CRTC3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 176-274) antibodyCRTC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D9 unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (Internal Region) antibodyCRTC3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 1-260) antibodyCRTC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) (AA 1-103) antibodyCRTC3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CREB Regulated Transcription Coactivator 3 (CRTC3) antibodyKD Validated CRTC3 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).
: "A new type of MAML2 fusion in mucoepidermoid carcinoma." in: Genes, chromosomes & cancer, Vol. 47, Issue 3, pp. 203-6, (2008) (PubMed).
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: "Clinicopathological significance of the CRTC3-MAML2 fusion transcript in mucoepidermoid carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 12, pp. 1575-81, (2009) (PubMed).
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- CRTC3 (CREB Regulated Transcription Coactivator 3 (CRTC3))
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别名
- CRTC3
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背景
- Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
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分子量
- 68 kDa
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基因ID
- 64784
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UniProt
- Q6UUV7
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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