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CIB1 抗体

This anti-CIB1 antibody is a 小鼠 单克隆 antibody detecting CIB1 in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969057
发货至: 中国

Quick Overview for CIB1 抗体 (ABIN969057)

抗原

See all CIB1 抗体
CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

适用

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宿主

  • 48
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小鼠

克隆类型

  • 53
  • 6
单克隆

标记

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This CIB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

5A1F5E12
  • 原理

    CIB1 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of CIB1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • White, Yang, Monteiro, Foskett: "CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel." in: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20825-33, (2006) (PubMed).

    Gentry, Singer, Betts, Yang, Ferrara, Sondek, Parise: "Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins." in: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8407-15, (2005) (PubMed).

  • 抗原

    CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

    别名

    CIB1

    背景

    CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21 kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.

    UniProt

    Q99828
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