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CDK9 抗体

This anti-CDK9 antibody is a 小鼠 单克隆 antibody detecting CDK9 in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969042
发货至: 中国

Quick Overview for CDK9 抗体 (ABIN969042)

抗原

See all CDK9 抗体
CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

适用

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宿主

  • 96
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小鼠

克隆类型

  • 86
  • 15
单克隆

标记

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This CDK9 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

1B5A7
  • 原理

    CDK9 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CDK9 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Montanuy, Torremocha, Hernández-Munain, Suñé: "Promoter influences transcription elongation: TATA-box element mediates the assembly of processive transcription complexes responsive to cyclin-dependent kinase 9." in: The Journal of biological chemistry, Vol. 283, Issue 12, pp. 7368-78, (2008) (PubMed).

    Sabò, Lusic, Cereseto, Giacca: "Acetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcription." in: Molecular and cellular biology, Vol. 28, Issue 7, pp. 2201-12, (2008) (PubMed).

  • 抗原

    CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

    别名

    CDK9

    背景

    The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. (provided by RefSeq)Tissue specificity: Ubiquitous.

    分子量

    43 kDa

    UniProt

    P50750

    途径

    Cell Division Cycle
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