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CD276 抗体

This anti-CD276 antibody is a 小鼠 单克隆 antibody detecting CD276 in ELISA, FACS 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969018
发货至: 中国

Quick Overview for CD276 抗体 (ABIN969018)

抗原

See all CD276 抗体
CD276

适用

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宿主

  • 55
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  • 7
  • 1
  • 1
小鼠

克隆类型

  • 49
  • 34
  • 1
单克隆

标记

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  • 1
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This CD276 antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

克隆位点

6A1
  • 原理

    CD276 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CD276 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Zhang, Dong, Xu, Yu, Zhang: "B7-H3: another molecule marker for Mo-DCs?" in: Cellular & molecular immunology, Vol. 2, Issue 4, pp. 307-11, (2005) (PubMed).

    Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

  • 抗原

    CD276

    别名

    CD276

    背景

    Costimulatory B7 Molecules (e.g., B7-1, or CD80, MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

    分子量

    57 kDa

    UniProt

    Q5ZPR3

    途径

    Cancer Immune Checkpoints
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