BMPR2 抗体
(2 references)Quick Overview for BMPR2 抗体 (ABIN968988)
抗原
See all BMPR2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- BMPR2 Antibody
-
纯化方法
- Ascitic fluid
-
免疫原
- Purified recombinant fragment of human BMPR2 expressed in E. Coli.
-
亚型
- IgG1
-
-
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) antibody
BMPR2 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1F12 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 28-59) antibodyBMPR2 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-150) antibodyBMPR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-150) antibodyBMPR2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 28-59), (N-Term) antibodyBMPR2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01778 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-150) antibodyBMPR2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-56), (N-Term) antibodyBMPR2 适用: 人, 小鼠 FACS, IHC (p) 宿主: 兔 Polyclonal RB1806 unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (Internal Region) antibodyBMPR2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (C-Term) antibodyKO Validated BMPR2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-56) antibodyBMPR2 适用: 人, 小鼠 ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/10000
ICC: 1/200 - 1/1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension." in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, Vol. 27, Issue 6, pp. 668-74, (2008) (PubMed).
: "Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension." in: Genetics in medicine : official journal of the American College of Medical Genetics, Vol. 10, Issue 5, pp. 359-65, (2008) (PubMed).
-
: "Clinical implications of determining BMPR2 mutation status in a large cohort of children and adults with pulmonary arterial hypertension." in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, Vol. 27, Issue 6, pp. 668-74, (2008) (PubMed).
-
- BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
-
别名
- BMPR2
-
背景
- This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. (provided by RefSeq)
-
分子量
- 115 kDa
-
基因ID
- 659
-
UniProt
- Q13873
-
途径
- Growth Factor Binding
抗原
-
