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BMP4 抗体

This anti-BMP4 antibody is a 小鼠 单克隆 antibody detecting BMP4 in ELISA. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN968986
发货至: 中国

Quick Overview for BMP4 抗体 (ABIN968986)

抗原

See all BMP4 抗体
BMP4 (Bone Morphogenetic Protein 4 (BMP4))

适用

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宿主

  • 121
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小鼠

克隆类型

  • 129
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单克隆

标记

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This BMP4 antibody is un-conjugated

应用范围

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ELISA

克隆位点

10F4B4
  • 原理

    BMP4 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human BMP4 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Solmesky, Abekasis, Bulvik, Weil: "Bone morphogenetic protein signaling is involved in human mesenchymal stem cell survival in serum-free medium." in: Stem cells and development, Vol. 18, Issue 9, pp. 1283-92, (2009) (PubMed).

    Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).

  • 抗原

    BMP4 (Bone Morphogenetic Protein 4 (BMP4))

    别名

    BMP4

    背景

    The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

    分子量

    64 kDa

    基因ID

    652

    UniProt

    P12644

    途径

    Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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