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Aurora A 抗体

This anti-Aurora A antibody is a 小鼠 单克隆 antibody detecting Aurora A in WB, ELISA, ICC 和 FACS. Suitable for 人, 大鼠 和 猴. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN968971
发货至: 中国

Quick Overview for Aurora A 抗体 (ABIN968971)

抗原

See all Aurora A (AURKA) 抗体
Aurora A (AURKA) (Aurora Kinase A (AURKA))

适用

  • 118
  • 68
  • 40
  • 21
  • 18
  • 15
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
人, 大鼠, 猴

宿主

  • 115
  • 18
  • 1
小鼠

克隆类型

  • 105
  • 28
单克隆

标记

  • 85
  • 8
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aurora A antibody is un-conjugated

应用范围

  • 99
  • 54
  • 39
  • 29
  • 16
  • 13
  • 11
  • 11
  • 9
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

克隆位点

1F8
  • 原理

    AURKA Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human AURKA expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Veerakumarasivam, Goldstein, Saeb-Parsy, Scott, Warren, Thorne, Mills, Venkitaraman, Neal, Kelly: "AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma." in: Cell cycle (Georgetown, Tex.), Vol. 7, Issue 22, pp. 3525-33, (2008) (PubMed).

    De Luca, Brunetto, Asteriti, Giubettini, Lavia, Guarguaglini: "Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity." in: Oncogene, Vol. 27, Issue 51, pp. 6539-49, (2008) (PubMed).

  • 抗原

    Aurora A (AURKA) (Aurora Kinase A (AURKA))

    别名

    AURKA

    背景

    Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

    分子量

    48 kDa

    UniProt

    O14965

    途径

    Cell Division Cycle, Asymmetric Protein Localization
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