Smooth Muscle Actin 抗体
Quick Overview for Smooth Muscle Actin 抗体 (ABIN968947)
抗原
See all Smooth Muscle Actin (ACTA2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- ACTA2 Antibody
-
纯化方法
- Ascitic fluid
-
免疫原
- Synthesized peptide of human ACTA2.
-
亚型
- IgG1
-
-
-
-
应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "ACTA2 is not a major disease-causing gene for moyamoya disease." in: Journal of human genetics, Vol. 54, Issue 11, pp. 687-8, (2009) (PubMed).
: "Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD)." in: Human mutation, Vol. 30, Issue 10, pp. 1406-11, (2009) (PubMed).
-
: "ACTA2 is not a major disease-causing gene for moyamoya disease." in: Journal of human genetics, Vol. 54, Issue 11, pp. 687-8, (2009) (PubMed).
-
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
-
别名
- ACTA2
-
背景
- The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.
-
分子量
- 42 kDa
-
基因ID
- 59
-
UniProt
- P62736
-
途径
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
抗原
-