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ABL2 抗体

This anti-ABL2 antibody is a 小鼠 单克隆 antibody detecting ABL2 in ELISA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN968943
发货至: 中国

Quick Overview for ABL2 抗体 (ABIN968943)

抗原

See all ABL2 抗体
ABL2

适用

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宿主

  • 82
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小鼠

克隆类型

  • 75
  • 14
单克隆

标记

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This ABL2 antibody is un-conjugated

应用范围

  • 53
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ELISA, Immunocytochemistry (ICC)

克隆位点

1H1B11
  • 原理

    ABL2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of ABL2 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Scheijen, Griffin: "Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease." in: Oncogene, Vol. 21, Issue 21, pp. 3314-33, (2002) (PubMed).

    Iijima, Ito, Oikawa, Eguchi, Eguchi-Ishimae, Kamada, Kishi, Asano, Sakaki, Sato: "A new ETV6/TEL partner gene, ARG (ABL-related gene or ABL2), identified in an AML-M3 cell line with a t(1;12)(q25;p13) translocation." in: Blood, Vol. 95, Issue 6, pp. 2126-31, (2000) (PubMed).

  • 抗原

    ABL2

    别名

    ABL2

    背景

    ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization,c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.

    基因ID

    27

    UniProt

    P42684
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