KIF3A 抗体 (AA 563-671)
(3 references)Quick Overview for KIF3A 抗体 (AA 563-671) (ABIN968567)
抗原
See all KIF3A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 563-671
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交叉反应
- 大鼠, 小鼠
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产品特性
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1. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
4. Please refer to us for technical protocols. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human KIF3A aa. 563-671
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亚型
- IgG1
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anti-Kinesin Family Member 3A (KIF3A) (AA 430-699) antibody
KIF3A 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (AA 430-699) antibodyKIF3A 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) antibodyKIF3A 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) antibodyKIF3A 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (AA 1-702) antibodyKIF3A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (C-Term) antibodyKIF3A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) antibodyKIF3A 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) antibodyKIF3A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (C-Term) antibodyKIF3A 适用: 人, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Kinesin Family Member 3A (KIF3A) (C-Term) antibodyKIF3A 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 5043-8, (1999) (PubMed).
: "The kinesin motor KIF3A is a component of the presynaptic ribbon in vertebrate photoreceptors." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 3, pp. 1027-37, (1999) (PubMed).
: "Kinesin and dynein superfamily proteins and the mechanism of organelle transport." in: Science (New York, N.Y.), Vol. 279, Issue 5350, pp. 519-26, (1998) (PubMed).
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: "Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 5043-8, (1999) (PubMed).
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- KIF3A (Kinesin Family Member 3A (KIF3A))
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别名
- KIF3A
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背景
- The ability of the kinesin superfamily of motor proteins to hydrolyze ATP as they move progressively along microtubules is important for organelle transport and cell division. Kinesins are grouped according to the location of the motor domain in the N-terminal, middle, or C-terminal region of the protein. A family of N-terminal motor domain kinesin proteins includes KIF3A/3B, KRP85/95, and Klp68d/64. These proteins form heterodimeric two-headed motors that interact with kinesin associated protein (KAP). The KIF3A/3B/KAP3 heterotrimeric motor has plus-end directed microtubule sliding activity. This heterotrimeric motor is expressed ubiquitously and is used for anterograde transport of membranous organelles. KIF3A- and KIF3B-deficient mice have defects in the formation of the cilia located in the embryonic node. In addition, KIF3A localizes to the basal body of the connecting cilium axoneme and to vesicles at the pre-synaptic ribbon in photoreceptor cells. Thus, KIF3 motors are involved in microtubule-based formation and movement of cilia and the transport of synaptic vesicles. This antibody is routinely tested by the Western blot analysis.
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分子量
- 80/85 kDa
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途径
- Hedgehog Signaling
抗原
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