RAB8A 抗体 (AA 84-205)
(5 references)Quick Overview for RAB8A 抗体 (AA 84-205) (ABIN968210)
抗原
See all RAB8A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 84-205
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交叉反应
- 犬, 小鼠, 大鼠, Fruit Fly (Drosophila melanogaster)
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human Rab8 aa. 84-205
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亚型
- IgG2b
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anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 108-207) antibody
RAB8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 68-207) antibodyRAB8A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G8B11 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22933 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 101-207) antibodyRAB8A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 8A4 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (C-Term) antibodyRAB8A 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 小鸡, 马, 猴, 山羊, 豚鼠, Avian, Cat, 驴, Hamster, 兔 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 170-183), (C-Term) antibodyRAB8A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (Middle Region) antibodyRAB8A 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968537, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "Rab27a: A key to melanosome transport in human melanocytes." in: The Journal of cell biology, Vol. 152, Issue 4, pp. 843-50, (2001) (PubMed).
: "Rab27a regulates the peripheral distribution of melanosomes in melanocytes." in: The Journal of cell biology, Vol. 152, Issue 4, pp. 795-808, (2001) (PubMed).
: "Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation." in: Molecular biology of the cell, Vol. 11, Issue 1, pp. 393-412, (2000) (PubMed).
: "Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line." in: Molecular and cellular biology, Vol. 10, Issue 12, pp. 6578-85, (1991) (PubMed).
: "The MEL gene: a new member of the RAB/YPT class of RAS-related genes." in: Oncogene, Vol. 6, Issue 8, pp. 1347-51, (1991) (PubMed).
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: "Rab27a: A key to melanosome transport in human melanocytes." in: The Journal of cell biology, Vol. 152, Issue 4, pp. 843-50, (2001) (PubMed).
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- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
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别名
- Rab8
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背景
- The members of the Ras superfamily of GTPases, which now includes more than 50 different proteins, shuttle between the GDP-bound inactive position and the GTP-bound active state. The GTPase activity of the Ras-like proteins is regulated by effectors that promote either the GDP- or the GTP-bound states. GTPases of the Ras superfamily have a role in controlling numerous events such as cell proliferation, nucleocytoplasmic transport, and vesicular traffic. The Rab superfamily of proteins includes more than 30 different members that are involved in the regulation of different steps of vesicular traffic. Subcellular localization and specific cellular function of each Rab appears to be encoded in the unique C-terminal part of the proteins, known as the hypervariable region. The 207 amino acid Rab8 protein is closely related to the yeast Sec4p and regulates vesicle transport from the Trans-golgi Network to the basolateral plasma membrane in epithelial cells. In addition, Rab8 interacts with the stress-activated kinase rab8p, a close homologue of the GC Kinase. This interaction was found to be dependent on GTP. This antibody is routinely tested by western blot analysis.
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分子量
- 24 kDa
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途径
- M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
抗原
-
