HAX1 抗体 (AA 10-148)
(1 reference)Quick Overview for HAX1 抗体 (AA 10-148) (ABIN968198)
抗原
See all HAX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 10-148
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交叉反应
- 大鼠, 小鼠
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human HAX-1 aa. 10-148
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亚型
- IgG1
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anti-HCLS1 Associated Protein X-1 (HAX1) antibody
HAX1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 2-250) antibodyHAX1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 76-174) antibodyHAX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 1-279) antibodyHAX1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 1-279) antibodyHAX1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (C-Term) antibodyHAX1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) antibodyHAX1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 191-279) antibodyHAX1 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (AA 107-156) antibodyHAX1 适用: 人, 小鼠, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-HCLS1 Associated Protein X-1 (HAX1) (N-Term) antibodyHAX1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968537, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 6, pp. 2736-44, (1997) (PubMed).
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: "HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 6, pp. 2736-44, (1997) (PubMed).
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- HAX1 (HCLS1 Associated Protein X-1 (HAX1))
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别名
- HAX-1
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背景
- Cell-cell interactions in the immune system, mediated by membrane-bound antigen receptors, trigger a cascade of signaling mechanisms collectively known as the T-cell response. Upon antigen binding, cellular tyrosine kinases are activated resulting in the phosphorylation of HS1 or Lck-binding protein 1 (LckBP1), which is involved in thymic negative selection. HS1 is one of the earliest intracellular proteins to be tyrosine phosphorylated in response to antigen-receptor cross-linking in T cells. HAX-1 (HS1-associated protein X-1) is a 35 kDa protein found associated with HS1 by co-immunoprecipitation assays and the two-hybrid system. HAX-1 is ubiquitously expressed and localized in the mitochondria, endoplasmic reticulum, and the nuclear envelope. The HS1-HAX-1 complex may be critical for signal transduction pathways initiated by antigen presentation to T cells.
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分子量
- 35 kDa
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途径
- Regulation of Actin Filament Polymerization
抗原
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