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Plakophilin 2 抗体 (AA 19-183)

PKP2 适用: 人 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 28-Plakophilin unconjugated
产品编号 ABIN968178
发货至: 中国
  • 抗原 See all Plakophilin 2 (PKP2) 抗体
    Plakophilin 2 (PKP2)
    抗原表位
    • 14
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-183
    适用
    • 51
    • 20
    • 20
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 44
    • 4
    • 2
    • 1
    小鼠
    克隆类型
    • 47
    • 4
    单克隆
    标记
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Plakophilin 2 antibody is un-conjugated
    应用范围
    • 37
    • 24
    • 22
    • 6
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human Plakophilin 2a aa. 19-183
    克隆位点
    28-Plakophilin
    亚型
    IgG1
    Top Product
    Discover our top product PKP2 Primary Antibody
  • 说明

    Related Products: ABIN968587, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Mertens, Kuhn, Franke: "Plakophilins 2a and 2b: constitutive proteins of dual location in the karyoplasm and the desmosomal plaque." in: The Journal of cell biology, Vol. 135, Issue 4, pp. 1009-25, (1997) (PubMed).

  • 抗原
    Plakophilin 2 (PKP2)
    别名
    Plakophilin 2 (PKP2 产品)
    别名
    ARVD9 antibody, 1200008D14Rik antibody, 1200012P04Rik antibody, AA516617 antibody, Pkp2l antibody, plakophilin 2 antibody, PKP2 antibody, Pkp2 antibody
    背景
    Plakophilin 2 is a desmosomal plaque protein that belongs to the arm repeat family of proteins. Alternative splicing results in two isoforms: 2a (837 aa) and 2b (881 aa). The 2b isoform contains an insertion of 44 aa in the arm repeat unit 2. Other arm family members are ß-catenin, plakophilin 1, plakoglobin, pp120, and armadillo of Drosophila gene product. They have at least 9 repeats of the arm motif, which consists of approximately 42 aa, and a short carboxyl terminus. Plakophilins are constitutively expressed in desmosome-containing cells. Plakophilin 1 has been found only in desmosomal-containing cells, such as stratified and complex epithelia. Plakophilin 2 has been isolated from both desmosomal as well as non-desmosomal forming cells, including simple and glandular epithelia, and from nonepithelial tissues such as the mycocardium and Purkinje fibers. In addition, Plakophilin 2 is found in the karyoplasm of interphase cells. Plakophilins 2a and 2b are part of desmosomal plaques, although they are located primarily in the karyoplasm of the interphase nucleus. The function of nuclear plakophilin 2 remains to be identified.
    分子量
    100 kDa
    途径
    Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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