HMOX1 抗体 (AA 150-286)
(4 references)Quick Overview for HMOX1 抗体 (AA 150-286) (ABIN968130)
抗原
See all HMOX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 150-286
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human Heme Oxygenase 1 (HO-1) aa. 150-286
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亚型
- IgG1
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anti-Heme Oxygenase (Decycling) 1 (HMOX1) antibody
KO Validated HMOX1 适用: 人 WB, ELISA, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-288) antibodyHMOX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Heme Oxygenase (Decycling) 1 (HMOX1) antibodyHMOX1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibodyHMOX1 适用: 人 WB, IHC, IP, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 1F12-A6 unconjugated
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody (HRP)HMOX1 适用: 人 WB, IHC, IP, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 1F12-A6 HRP
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (N-Term) antibodyHMOX1 适用: 人, 大鼠, 小鼠, Pig, 犬, Cow, 豚鼠, 兔, 山羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 99-237) antibodyHMOX1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 61-172) antibodyHMOX1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A4 unconjugated
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 61-172) antibodyHMOX1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-30) antibody (FITC)HMOX1 适用: 人 WB, IHC, IP, ELISA, ICC, IF 宿主: 小鼠 Monoclonal 1F12-A6 FITC
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "Pressurization facilitates adenovirus-mediated gene transfer into vein graft." in: FEBS letters, Vol. 470, Issue 3, pp. 370-4, (2000) (PubMed).
: "Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. Involvement of superoxide and peroxynitrite anions." in: The Journal of biological chemistry, Vol. 272, Issue 29, pp. 18411-7, (1997) (PubMed).
: "Induction of heme oxygenase-1 inhibits the monocyte transmigration induced by mildly oxidized LDL." in: The Journal of clinical investigation, Vol. 100, Issue 5, pp. 1209-16, (1997) (PubMed).
: "Human heme oxygenase cDNA and induction of its mRNA by hemin." in: European journal of biochemistry / FEBS, Vol. 171, Issue 3, pp. 457-61, (1988) (PubMed).
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: "Pressurization facilitates adenovirus-mediated gene transfer into vein graft." in: FEBS letters, Vol. 470, Issue 3, pp. 370-4, (2000) (PubMed).
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- HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))
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别名
- Heme Oxygenase 1
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背景
- Heme oxygenases 1 and 2 (HO-1, HO-2) cleave the heme molecule, resulting in the production of carbon monoxide (CO) and biliverdin. HO-1 is a 288 amino acid monooxygenase with a molecular weight of 32 kDa. While HO-2 is constitutively expressed in tissues, HO-1 is rapidly induced by several stimuli such as lutathione depletion, hemin, heat shock, heavy metals, oxidative stress, oxidized LDL, anoxia, and endotoxic shock. Similar to nitric oxide (NO), CO activates guanylate cyclase and reduces platelet aggregation. Several conditions that increase NO also induce HO-1 expression and activity. This suggests that NO synthases, Cox-2, and HO-1 are part of a general defense mechanism against stress and pathogen invasion.
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分子量
- 32 kDa
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
抗原
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