NUMA1 抗体 (AA 10-189)
(4 references)Quick Overview for NUMA1 抗体 (AA 10-189) (ABIN968039)
抗原
See all NUMA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 10-189
-
交叉反应
- 小鼠, 大鼠, 小鸡, 犬
-
产品特性
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
免疫原
- Human NuMA aa. 10-189
-
亚型
- IgM
-
-
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-309) antibody
NUMA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (N-Term) antibodyNUMA1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 627-870) antibodyNUMA1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-1193) antibodyNUMA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1-1193) antibodyNUMA1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 200-306) antibodyNUMA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) antibodyNUMA1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (N-Term) antibodyNUMA1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1700-2115) antibodyNUMA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Mitotic Apparatus Protein 1 (NUMA1) (AA 1700-2115) antibodyNUMA1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D9 unconjugated
-
-
说明
-
Related Products: ABIN968535, ABIN967389
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 250 μg/mL
-
缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store undiluted at -20°C.
-
-
-
: "Recruitment of dioxin receptor to active transcription sites." in: Molecular biology of the cell, Vol. 13, Issue 6, pp. 2001-15, (2002) (PubMed).
: "Expression, cellular distribution and protein binding of the glioma amplified sequence (GAS41), a highly conserved putative transcription factor." in: Oncogene, Vol. 20, Issue 35, pp. 4853-63, (2001) (PubMed).
: "A kinase-anchoring protein (AKAP)95 recruits human chromosome-associated protein (hCAP)-D2/Eg7 for chromosome condensation in mitotic extract." in: The Journal of cell biology, Vol. 149, Issue 3, pp. 531-6, (2000) (PubMed).
: "NuMA: an unusually long coiled-coil related protein in the mammalian nucleus." in: The Journal of cell biology, Vol. 116, Issue 6, pp. 1303-17, (1992) (PubMed).
-
: "Recruitment of dioxin receptor to active transcription sites." in: Molecular biology of the cell, Vol. 13, Issue 6, pp. 2001-15, (2002) (PubMed).
-
- NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))
-
别名
- NuMA
-
背景
- NuMA (Nuclear Mitotic Apparatus protein) is a 2115 amino acid protein with a coiled-coil structure similar to that of myosins and intermediate filaments. Indirect immunofluorescence assays indicate that NuMA's localization is very dynamic. During interphase, NuMA is in the nucleus and during mitosis it moves to the polar regions of the mitotic spindle. NuMA is a very abundant phosphoprotein and antibodies to this protein are often found in patients with autoimmune diseases. Although NuMA is thought to be a structural component of the nucleus, the precise cellular function for this protein is still unknown.
-
分子量
- 238-290 kDa
-
途径
- Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase
抗原
-
