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CK1 epsilon 抗体 (AA 248-414)

CSNK1E 适用: 人, 小鼠, 大鼠, 犬, 小鸡 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 1-Casein Kinase Iepsilon unconjugated
产品编号 ABIN967975
发货至: 中国
  • 抗原 See all CK1 epsilon (CSNK1E) 抗体
    CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
    抗原表位
    • 10
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 248-414
    适用
    • 59
    • 41
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 小鸡
    宿主
    • 60
    • 7
    • 2
    • 1
    小鼠
    克隆类型
    • 63
    • 7
    单克隆
    标记
    • 37
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CK1 epsilon antibody is un-conjugated
    应用范围
    • 47
    • 33
    • 32
    • 13
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    小鼠, 大鼠, 小鸡, 犬
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Please refer to us for technical protocols.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Human Casein Kinase Iepsilon aa. 248-414
    克隆位点
    1-Casein Kinase Iepsilon
    亚型
    IgG1
    Top Product
    Discover our top product CSNK1E Primary Antibody
  • 说明

    Related Products: ABIN968536, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Akashi, Tsuchiya, Yoshino, Nishida: "Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells." in: Molecular and cellular biology, Vol. 22, Issue 6, pp. 1693-703, (2002) (PubMed).

    Kishida, Hino Si, Michiue, Yamamoto, Kishida, Fukui, Asashima, Kikuchi: "Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon." in: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 33147-55, (2001) (PubMed).

    Peters, McKay, McKay, Graff: "Casein kinase I transduces Wnt signals." in: Nature, Vol. 401, Issue 6751, pp. 345-50, (1999) (PubMed).

    Fish, Cegielska, Getman, Landes, Virshup: "Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family." in: The Journal of biological chemistry, Vol. 270, Issue 25, pp. 14875-83, (1995) (PubMed).

  • 抗原
    CK1 epsilon (CSNK1E) (Casein Kinase 1, epsilon (CSNK1E))
    别名
    Casein Kinase Iepsilon (CSNK1E 产品)
    别名
    CKIepsilon antibody, HCKIE antibody, CKIe antibody, ck1-epsilon antibody, ck1epsilon antibody, hckie antibody, dco antibody, fj38c01 antibody, wu:fj38c01 antibody, wu:fj62a04 antibody, zgc:77310 antibody, AI426939 antibody, AI551861 antibody, AW457082 antibody, CK1epsilon antibody, KC1epsilon antibody, tau antibody, ckie antibody, CSNK1E antibody, Csnk1e antibody, CKI-epsilon antibody, 0538/13 antibody, 0915/10 antibody, 1396/02 antibody, 1447/01 antibody, 1460/09 antibody, CG2048 antibody, CK1delta/epsilon antibody, DBT antibody, DBT/CK1epsilon antibody, DCO antibody, DCO/CKIe antibody, Dbt antibody, Dco antibody, Dco/CK1 antibody, Dmel\CG2048 antibody, dCKIepsilon antibody, dbt antibody, dco-1 antibody, ddbt antibody, l(3)S053813 antibody, l(3)S144701 antibody, l(3)dco antibody, l(3)dco-1 antibody, l(3)discs overgrown antibody, l(3)discs overgrown-1 antibody, l(3)j3B9 antibody, l(3)rK215 antibody, casein kinase 1 epsilon antibody, casein kinase 1, epsilon antibody, casein kinase 1 epsilon L homeolog antibody, casein kinase I isoform epsilon antibody, casein kinase I epsilon antibody, casein kinase I antibody, LOC400927-CSNK1E readthrough antibody, discs overgrown antibody, CSNK1E antibody, csnk1e antibody, Csnk1e antibody, csnk1e.L antibody, LOC443240 antibody, NAEGRDRAFT_82890 antibody, LOC100407384 antibody, LOC100523244 antibody, LOC100607246 antibody, LOC100727500 antibody, LOC400927-CSNK1E antibody, dco antibody
    背景
    Casein Kinase Iepsilon (CKIepsilon) is a product of a family of proteins involved in the regulation of various cytoplasmic and nuclear processes including DNA replication and repair. CKIepsilon is a 47.3 kDa serine/threonine kinase that plays a role similar to previously described CKI isoforms. It phosphorylates known CKI substrates, including a CKI-specific peptide. In addition, it is inhibited by CKI-7, an inhibitor of other CKI isoforms. CKIepsilon contains a core kinase domain of 285 amino acids which is 53-98% identical to other isoforms and is most similiar in structure to CKIdelta. Since various human and yeast CKI proteins exhibit both sequence and functional similarities, CKIepsilon may be involved in mammalian DNA metabolism.
    分子量
    47 kDa
    途径
    Hedgehog Signaling, M Phase
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