TIAL1 抗体 (AA 161-365)
(2 references)Quick Overview for TIAL1 抗体 (AA 161-365) (ABIN967917)
抗原
See all TIAL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 161-365
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交叉反应
- 小鼠, 大鼠, 犬, Frog
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human TIAR aa. 161-365
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亚型
- IgG1
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anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) antibody
TIAL1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 266-375) antibodyTIAL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 1-252) antibodyTIAL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 1-90) antibodyTIAL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (Internal Region) antibodyVerified TIAL1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (Internal Region) antibodyTIAL1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 9-277) antibodyTIAL1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (AA 275-325) antibodyTIAL1 适用: 人, 小鼠 IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) antibodyTIAL1 适用: 人, 小鼠, Non-Human Primate WB, ELISA, IHC (p), FACS, ICC 宿主: 小鼠 Monoclonal 6E3 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1) (C-Term) antibodyTIAL1 适用: 人, 小鼠, 大鼠, 犬, 兔, 斑马鱼, Cow, 豚鼠, 马, 小鸡, Bat, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968555, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1629-33, (1995) (PubMed).
: "Identification and functional characterization of a TIA-1-related nucleolysin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8681-5, (1992) (PubMed).
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: "The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 5, pp. 1629-33, (1995) (PubMed).
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- TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
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别名
- TIAR
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背景
- TIAR is an RNA-binding protein related to TIA-1. Both proteins are candidate effectors of apoptotic cell death and consist of three N-terminal RNA-recognition motifs (RRM) and a C-terminal protein-interaction domain (PID). Unlike TIA-1, which is localized in the granules of cytotoxic lymphocytes, TIAR is predominantly found in the nucleus of many different cell types. Two related isoforms (42 kDa and 50 kDa) of TIAR have been identified. It has been demonstrated that TIAR can trigger DNA fragmentation in permeabilized thymocytes, suggesting that it may be an effector of apoptotic cell death. During Fas-mediated apoptosis, TIAR shows a rapid translocation from the nucleus to the cytoplasm. This redistribution of TIAR appears to be a specific event and possibly a general feature of the apoptotic program.
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分子量
- 50 & 42 kDa
抗原
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