AKAP5 抗体 (AA 180-427)
(4 references)Quick Overview for AKAP5 抗体 (AA 180-427) (ABIN967900)
抗原
See all AKAP5 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 180-427
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human AKAP79 aa. 180-427
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亚型
- IgG1
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anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) (N-Term) antibody
AKAP5 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) (AA 1-270) antibodyAKAP5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) (AA 334-427) antibodyAKAP5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) (AA 611-714) antibodyAKAP5 适用: 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) (N-Term) antibodyAKAP5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) antibodyAKAP5 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) (C-Term) antibodyAKAP5 适用: 人, 大鼠, 小鼠, Cow, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) (AA 1-270) antibodyAKAP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 5 (AKAP5) (AA 1-50) antibodyAKAP5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968552, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20°C.
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: "Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 4, pp. 1590-9, (2002) (PubMed).
: "cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 17, pp. 7486-94, (1999) (PubMed).
: "Association of protein kinase A and protein phosphatase 2B with a common anchoring protein." in: Science (New York, N.Y.), Vol. 267, Issue 5194, pp. 108-11, (1995) (PubMed).
: "Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79." in: The Journal of biological chemistry, Vol. 267, Issue 24, pp. 16816-23, (1992) (PubMed).
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: "Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 4, pp. 1590-9, (2002) (PubMed).
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- AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))
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别名
- AKAP79
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背景
- The type II cAMP-dependent Protein Kinase (PKA) is compartmentalized within the cell. To maintain this localization of type II PKAs, the regulatory subunit (RII) interacts with specific RII-anchoring proteins. For instance, attachment of type II PKA to the cytoskeleton occurs through the binding of RII to microtubule-associated protein 2 (MAP2). In brain, several proteins have been identified as PKA type II anchoring proteins and form a family named AKAP (A-Kinase Anchor Proteins). AKAP79 is a 79kDa human RII-anchoring protein. AKAP, PKA type II, and calcineurin (PP2B) can form a tertiary complex, suggesting that both PKA and calcineurin are targeted by a common protein to subcellular sites where they regulate the phosphorylation status of key substrates.
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分子量
- 79 kDa
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途径
- cAMP Metabolic Process
抗原
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