CD24 抗体
Quick Overview for CD24 抗体 (ABIN967323)
抗原
See all CD24 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- BD Pharmingen™
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Rat bone marrow cells
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亚型
- IgM kappa
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store undiluted at 4°C.
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: "Expression of HIS50 Ag: a rat homologue of mouse heat-stable antigen and human CD24 on B lymphoid cells in the rat." in: Immunology, Vol. 90, Issue 1, pp. 14-22, (1997) (PubMed).
: "Characterization of rat HSA/CD24 protein bearing the B lineage-restricted epitope recognized by MAb HIS50." in: Hybridoma, Vol. 15, Issue 1, pp. 33-42, (1997) (PubMed).
: "Gene expression of CD24 core polypeptide molecule in normal rat tissues and human tumor cell lines." in: Virchows Archiv : an international journal of pathology, Vol. 425, Issue 4, pp. 399-406, (1995) (PubMed).
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: "Expression of HIS50 Ag: a rat homologue of mouse heat-stable antigen and human CD24 on B lymphoid cells in the rat." in: Immunology, Vol. 90, Issue 1, pp. 14-22, (1997) (PubMed).
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- CD24 (CD24 Molecule (CD24))
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别名
- CD24
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背景
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The HIS50 antibody reacts with CD24 (Heat-Stable Antigen, HSA or HsAg), a variably glycosylated GPI-anchored membrane protein. In the rat, Cd24 mRNA is found in a variety of epithelia, neural tissue, lymph node germinal centers, and thymus. mAb HIS50 detects CD24 on most B-lineage cells in the bone marrow, on most sIgM[high] B lymphocytes in the blood and spleen, and on marginal-zone B cells in the spleen and lymph node. Variable levels of CD24 are detected on sIgM[dull] and follicular B lymphocytes. mAb HIS50 does not detect CD24 on rat thymocytes nor peripheral T lymphocytes, NK cells, or granulocytes. The HIS50 antibody cross-reacts with intracellular antigen(s) in human lymphocytes.
Synonyms: Heat-Stable Antigen -
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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