电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Vimentin 抗体

This anti-Vimentin antibody is a 小鼠 单克隆 antibody detecting Vimentin in WB, IHC 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN967252
发货至: 中国

Quick Overview for Vimentin 抗体 (ABIN967252)

抗原

See all Vimentin (VIM) 抗体
Vimentin (VIM)

适用

  • 377
  • 130
  • 128
  • 63
  • 61
  • 49
  • 43
  • 38
  • 30
  • 22
  • 21
  • 13
  • 13
  • 8
  • 8
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 199
  • 164
  • 11
  • 6
  • 6
  • 5
  • 2
  • 2
小鼠

克隆类型

  • 203
  • 191
单克隆

标记

  • 241
  • 19
  • 13
  • 12
  • 9
  • 7
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
This Vimentin antibody is un-conjugated

应用范围

  • 328
  • 170
  • 126
  • 106
  • 94
  • 63
  • 63
  • 40
  • 39
  • 34
  • 33
  • 33
  • 23
  • 8
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

9E7E7-5G3F10-5G3F10E5
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of Vimentin expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Vanzi: "Freedom at home: state constitutions and Medicaid funding for abortions." in: New Mexico law review, Vol. 26, Issue 3, pp. 433-54, (2005) (PubMed).

  • 抗原

    Vimentin (VIM)

    别名

    Vimentin

    背景

    Vimentin is the major subunit protein of the intermediate filaments of mesenchymal cells. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis. Immunohistochemical staining for Vimentin is characteristic of sarcomas (of neural, muscle and fibroblast origin) compared to carcinomas which are generally negative. Melanomas, lymphomas and vascular tumors may all stain for Vimentin. Vimentin antibodies are thus of value in the differential diagnosis of undifferentiated neoplasms and malignant tumors. They are generally used with a panel of other antibodies including those recognising cytokeratins, lymphoid markers, S100, desmin and neurofilaments.
    Synonyms: FLJ36605, VIM

    基因ID

    7431

    途径

    Caspase Cascade in Apoptosis
You are here:
Chat with us!