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Vimentin 抗体 (C-Term)

VIM 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042344
发货至: 中国
  • 抗原 See all Vimentin (VIM) 抗体
    Vimentin (VIM)
    抗原表位
    • 32
    • 18
    • 16
    • 16
    • 16
    • 14
    • 11
    • 8
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    • 4
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    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 435-466, C-Term
    适用
    • 333
    • 126
    • 125
    • 61
    • 58
    • 43
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    • 36
    • 29
    • 21
    • 20
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    • 1
    • 1
    • 1
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    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 190
    • 129
    • 9
    • 6
    • 4
    • 4
    • 2
    克隆类型
    • 198
    • 145
    多克隆
    标记
    • 200
    • 19
    • 13
    • 13
    • 11
    • 7
    • 7
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    • 4
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    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Vimentin antibody is un-conjugated
    应用范围
    • 282
    • 132
    • 99
    • 98
    • 96
    • 65
    • 49
    • 40
    • 39
    • 28
    • 23
    • 20
    • 8
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Vimentin(VIM) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    DTHSKRTLLI KTVETRDGQV INETSQHHDD LE
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Vimentin(VIM) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: vimentin
    Protein Name: Vimentin
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human Vimentin (435-466aa DTHSKRTLLIKTVETRDGQVINETSQHHDDLE), identical to the related mouse and rat sequences.
    亚型
    IgG
    Top Product
    Discover our top product VIM Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Vimentin is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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    Xu, Xiao, Luo, Chen, Zhang, Tao, Jiang, Chen, Shen: "Inhibitory effects of oxymatrine on TGF‑β1‑induced proliferation and abnormal differentiation in rat cardiac fibroblasts via the p38MAPK and ERK1/2 signaling pathways." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 5354-5362, (2018) (PubMed).

    Bu, Zhang, Wang, Lai: "Human amniotic epithelial cells inhibit growth of epithelial ovarian cancer cells via TGF‑β1-mediated cell cycle arrest." in: International journal of oncology, Vol. 51, Issue 5, pp. 1405-1414, (2018) (PubMed).

    Gu, Fang, Kang, Hu, Yu, Li, Cheng, Gao: "Effect of ALDH2 on High Glucose-Induced Cardiac Fibroblast Oxidative Stress, Apoptosis, and Fibrosis." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 9257967, (2018) (PubMed).

    Zhang, Bu, Sun, Xu, Yao, He, Lai: "Paracrine effects of human amniotic epithelial cells protect against chemotherapy-induced ovarian damage." in: Stem cell research & therapy, Vol. 8, Issue 1, pp. 270, (2018) (PubMed).

    Huang, Zheng, Pan, Wu, Su, Li, Wu, Sun: "Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats." in: Scientific reports, Vol. 8, Issue 1, pp. 490, (2018) (PubMed).

    Ling, Zhou, Zhou, Dai, Wu, Mi, Mao, Chen: "Lin28/microRNA-let-7a promotes metastasis under circumstances of hyperactive Wnt signaling in esophageal squamous cell carcinoma." in: Molecular medicine reports, Vol. 17, Issue 4, pp. 5265-5271, (2018) (PubMed).

    Jia, Jiang, Liu, Wang, Zhu, Zhu, Liu, Zhong, Xie, Huang, Jia, Li, Liu, Zuo, Cheng, Dai, Ren: "Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells." in: International journal of oncology, Vol. 52, Issue 6, pp. 1787-1800, (2018) (PubMed).

    Zhang, Nguyen, Shi, Burrell, Cullen, Le: "3D bio-printed scaffold-free nerve constructs with human gingiva-derived mesenchymal stem cells promote rat facial nerve regeneration." in: Scientific reports, Vol. 8, Issue 1, pp. 6634, (2018) (PubMed).

    Wang, Xu, Fu, Chen, Yang: "The Antihelminthic Niclosamide Inhibits Cancer Stemness, Extracellular Matrix Remodeling, and Metastasis through Dysregulation of the Nuclear β-catenin/c-Myc axis in OSCC." in: Scientific reports, Vol. 8, Issue 1, pp. 12776, (2018) (PubMed).

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    Guo, Yu, Xu, Lian, Yu, Cui, Ji, Chen, Li, Liu, Chen: "PAC1R agonist maxadilan enhances hADSC viability and neural differentiation potential." in: Journal of cellular and molecular medicine, Vol. 20, Issue 5, pp. 874-90, (2017) (PubMed).

    Deng, Li, Lin, Huang, Zeng, Wang, Li, Jin, Zhang, Li, Chen, Wang, Huang, Shao, Xu, Mao: "P-glycoprotein Mediates Postoperative Peritoneal Adhesion Formation by Enhancing Phosphorylation of the Chloride Channel-3." in: Theranostics, Vol. 6, Issue 2, pp. 204-18, (2017) (PubMed).

    Zheng, Zou, Shen, Xu, Wang, Fu, Fan: "Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth." in: Stem cells translational medicine, Vol. 5, Issue 9, pp. 1216-28, (2017) (PubMed).

    Yu, Liu, Liang, Ochs, Chen, Chen, Du, Tang, Huang, Du, Jin: "Sulfur Dioxide Protects Against Collagen Accumulation in Pulmonary Artery in Association With Downregulation of the Transforming Growth Factor β1/Smad Pathway in Pulmonary Hypertensive Rats." in: Journal of the American Heart Association, Vol. 5, Issue 10, (2017) (PubMed).

    Wang, Tu, Zhang, Xu, Qian: "Stellate Cell Activation and Imbalanced Expression of TGF-β1/TGF-β3 in Acute Autoimmune Liver Lesions Induced by ConA in Mice." in: BioMed research international, Vol. 2017, pp. 2540540, (2017) (PubMed).

    Wei, Zhu, Xiang, Song, Guo, Lin, Li, Zeng: "Corticosterone suppresses IL-1β-induced mPGE2 expression through regulation of the 11β-HSD1 bioactivity of synovial fibroblasts in vitro." in: Experimental and therapeutic medicine, Vol. 13, Issue 5, pp. 2161-2168, (2017) (PubMed).

    Wang, An, Yu, Zhang, Tang, Zhang, Li: "MiR-29b/TET1/ZEB2 signaling axis regulates metastatic properties and epithelial-mesenchymal transition in breast cancer cells." in: Oncotarget, Vol. 8, Issue 60, pp. 102119-102133, (2017) (PubMed).

    Wu, Wang, Ji, Ou, Xia, Zhang, Zhao: "C4orf7 modulates osteogenesis and adipogenesis of human periodontal ligament cells." in: American journal of translational research, Vol. 9, Issue 12, pp. 5708-5718, (2017) (PubMed).

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  • 抗原
    Vimentin (VIM)
    别名
    VIM (VIM 产品)
    别名
    CTRCT30 antibody, cb28 antibody, vime antibody, vim antibody, vim1 antibody, vim2 antibody, VIM antibody, Vimentin antibody, vim4 antibody, vimentin antibody, vimentin L homeolog antibody, vimentin S homeolog antibody, VIM antibody, Vim antibody, vim antibody, vim.L antibody, vim.S antibody
    背景
    VIM(vimentin) is also known as HEL113 or CTRCT30. This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.

    Synonyms: CTRCT30 antibody|Epididymis luminal protein 113 antibody|FLJ36605 antibody|HEL113 antibody|VIM antibody|VIME_HUMAN antibody|vimentin antibody
    基因ID
    7431
    UniProt
    P08670
    途径
    Caspase Cascade in Apoptosis
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