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VAV1 抗体

This anti-VAV1 antibody is a 兔 多克隆 antibody detecting VAV1 in IHC. Suitable for 人, 大鼠 和 小鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN967242
发货至: 中国

Quick Overview for VAV1 抗体 (ABIN967242)

抗原

See all VAV1 抗体
VAV1 (Vav 1 Oncogene (VAV1))

适用

  • 67
  • 38
  • 24
  • 1
  • 1
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 66
  • 4

克隆类型

  • 65
  • 5
多克隆

标记

  • 51
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
This VAV1 antibody is un-conjugated

应用范围

  • 50
  • 35
  • 18
  • 9
  • 8
  • 8
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • 特异性

    Vav (Ab-174) antibody detects endogenous levels of total Vav protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human Vav around the phosphorylation site of tyrosine 174 (E-I-YP-E-D).
  • 应用备注

    WB: 1:500~1:1000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100ug/100ul.

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Amarasinghe, Rosen: "Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain." in: Biochemistry, Vol. 44, Issue 46, pp. 15257-68, (2005) (PubMed).

    Charvet, Canonigo, Billadeau, Altman: "Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76." in: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15289-99, (2005) (PubMed).

    Miura-Shimura, Duan, Rao, Reddi, Shimura, Rottapel, Druker, Tsygankov, Band, Band: "Cbl-mediated ubiquitinylation and negative regulation of Vav." in: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38495-504, (2003) (PubMed).

    Kuhne, Ku, Weiss: "A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation." in: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2185-90, (2000) (PubMed).

  • 抗原

    VAV1 (Vav 1 Oncogene (VAV1))

    别名

    Vav

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
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