TLR9 抗体 (N-Term)
Quick Overview for TLR9 抗体 (N-Term) (ABIN967190)
抗原
See all TLR9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Tlr9 (Toll-like receptor 9)
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限制
- 仅限研究用
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储存条件
- 4 °C
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A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors." in: International immunology, Vol. 20, Issue 11, pp. 1407-15, (2008) (PubMed).
: "Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 10, pp. 3516-21, (2004) (PubMed).
: "Toll-like receptor 9 mediates CpG-DNA signaling." in: Journal of leukocyte biology, Vol. 71, Issue 3, pp. 538-44, (2002) (PubMed).
: "Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 9237-42, (2001) (PubMed).
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A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors." in: International immunology, Vol. 20, Issue 11, pp. 1407-15, (2008) (PubMed).
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- TLR9 (Toll-Like Receptor 9 (TLR9))
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别名
- Tlr9
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背景
- Tlr9 (Toll-like receptor 9) participates in the innate immune response to microbial agents. Tlr9 (Toll-like receptor 9) detects the unmethylated cytidine-phosphate-guanosine (CpG) motifs present in bacterial DNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Tlr9 (Toll-like receptor 9) plays a role in defense against sytemic mouse cytomegalovirus infection. Tlr9 (Toll-like receptor 9) binds MYD88 via their respective TIR domains and interacts with CNPY3. Tlr9 (Toll-like receptor 9) belongs to the Toll-like receptor family and contains 26 LRR (leucine-rich) repeats and 1 TIR domain.
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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