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TLR9 抗体 (N-Term)

This anti-TLR9 antibody is a 兔 多克隆 antibody detecting TLR9 in IHC. Suitable for 小鼠. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN967190
发货至: 中国

Quick Overview for TLR9 抗体 (N-Term) (ABIN967190)

抗原

See all TLR9 抗体
TLR9 (Toll-Like Receptor 9 (TLR9))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This TLR9 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Tlr9 (Toll-like receptor 9)
  • 限制

    仅限研究用
  • 储存条件

    4 °C
  • Kiyokawa, Akashi-Takamura, Shibata, Matsumoto, Nishitani, Kuroki, Seto, Miyake: "A single base mutation in the PRAT4A gene reveals differential interaction of PRAT4A with Toll-like receptors." in: International immunology, Vol. 20, Issue 11, pp. 1407-15, (2008) (PubMed).

    Tabeta, Georgel, Janssen, Du, Hoebe, Crozat, Mudd, Shamel, Sovath, Goode, Alexopoulou, Flavell, Beutler: "Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 10, pp. 3516-21, (2004) (PubMed).

    Chuang, Lee, Kline, Mathison, Ulevitch: "Toll-like receptor 9 mediates CpG-DNA signaling." in: Journal of leukocyte biology, Vol. 71, Issue 3, pp. 538-44, (2002) (PubMed).

    Bauer, Kirschning, Häcker, Redecke, Hausmann, Akira, Wagner, Lipford: "Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 16, pp. 9237-42, (2001) (PubMed).

  • 抗原

    TLR9 (Toll-Like Receptor 9 (TLR9))

    别名

    Tlr9

    背景

    Tlr9 (Toll-like receptor 9) participates in the innate immune response to microbial agents. Tlr9 (Toll-like receptor 9) detects the unmethylated cytidine-phosphate-guanosine (CpG) motifs present in bacterial DNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Tlr9 (Toll-like receptor 9) plays a role in defense against sytemic mouse cytomegalovirus infection. Tlr9 (Toll-like receptor 9) binds MYD88 via their respective TIR domains and interacts with CNPY3. Tlr9 (Toll-like receptor 9) belongs to the Toll-like receptor family and contains 26 LRR (leucine-rich) repeats and 1 TIR domain.

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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