SRA1 抗体
(3 references)Quick Overview for SRA1 抗体 (ABIN967076)
抗原
See all SRA1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Ni-NTA purified truncated recombinant SRA expressed in E. Coli strain BL21 (DE3)
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纯化方法
- Crude ascites.
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亚型
- IgG1
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anti-Steroid Receptor RNA Activator 1 (SRA1) antibody
SRA1 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 1D4H8 unconjugated
anti-Steroid Receptor RNA Activator 1 (SRA1) (AA 92-141) antibodySRA1 适用: 人, 大鼠, Cow, 豚鼠, 马, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Steroid Receptor RNA Activator 1 (SRA1) (truncated) antibodySRA1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1D4H8 unconjugated
anti-Steroid Receptor RNA Activator 1 (SRA1) (AA 519-556) antibodySRA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IP 宿主: 小鼠 Monoclonal 30A4 unconjugated
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应用备注
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Western Blot: 1: 500- 1: 2,000
IHC(P): 1: 500- 1: 2,000
IHC(F): 1: 500- 1: 2,000
ELISA: Propose dilution 1: 10,000 Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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储存条件
- -20 °C
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: "The steroid receptor RNA activator protein is expressed in breast tumor tissues." in: International journal of cancer. Journal international du cancer, Vol. 118, Issue 4, pp. 1054-9, (2006) (PubMed).
: "The steroid receptor RNA activator is the first functional RNA encoding a protein." in: FEBS letters, Vol. 566, Issue 1-3, pp. 43-7, (2004) (PubMed).
: "Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo." in: Molecular and cellular biology, Vol. 23, Issue 20, pp. 7163-76, (2003) (PubMed).
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: "The steroid receptor RNA activator protein is expressed in breast tumor tissues." in: International journal of cancer. Journal international du cancer, Vol. 118, Issue 4, pp. 1054-9, (2006) (PubMed).
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- SRA1 (Steroid Receptor RNA Activator 1 (SRA1))
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别名
- SRA
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背景
- Steroid receptor RNA activator 1 (SRA), with 237-amino acid protein (about 27kDa), belongs to the growing family of functional non-coding RNAs. SRA was originally described as the first functional noncoding RNA able to specifically coactivate the activity of steroid receptors. Specifically, SRA exists as both an RNA transcript that forms a complex with steroid receptor coactivator-1 and as a stably expressed protein. Its expression is strongly up-regulated in many human tumors of the breast, uterus, and ovary, suggesting a potential role in pathogenesis. Although coactivation of steroid-dependent transcription by SRA is accompanied by a proliferative response, overexpression is not in itself sufficient to induce turmorigenesis.
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基因ID
- 10011
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途径
- EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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