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SNCG 抗体

SNCG 适用: 人 WB, IHC, ELISA Monoclonal unconjugated
产品编号 ABIN967062
发货至: 中国
  • 抗原 See all SNCG 抗体
    SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))
    适用
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    克隆类型
    • 50
    • 15
    单克隆
    标记
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    This SNCG antibody is un-conjugated
    应用范围
    • 42
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3)
    纯化方法
    Antibodies are purified by protein A affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product SNCG Primary Antibody
  • 应用备注
    Western Blot: 1: 500- 1: 2,000
    IHC(P): 1: 500- 1: 2,000
    IHC(F): 1: 500- 1: 2,000
    ELISA: Propose dilution 1: 10,000.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 储存条件
    -20 °C
  • Surgucheva, McMahon, Surguchov: "gamma-synuclein has a dynamic intracellular localization." in: Cell motility and the cytoskeleton, Vol. 63, Issue 8, pp. 447-58, (2006) (PubMed).

  • 抗原
    SNCG (Synuclein, gamma (Breast Cancer-Specific Protein 1) (SNCG))
    Abstract
    SNCG 产品
    背景
    SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein. Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
    基因ID
    6623
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