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SETDB1 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-SETDB1 antibody is suitable to detect SETDB1 in samples from 人, 小鼠 和 猴. It has been validated for WB 和 ELISA.
产品编号 ABIN967016
发货至: 中国
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Quick Overview for SETDB1 抗体 (ABIN967016)

抗原

See all SETDB1 抗体
SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

适用

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人, 小鼠, 猴

宿主

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小鼠

克隆类型

  • 43
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单克隆

标记

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This SETDB1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

5H6D4
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human SETDB1 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Gao, Yu, Bi, Jiang, Cui, Sun, Ma: "Akt/PKB interacts with the histone H3 methyltransferase SETDB1 and coordinates to silence gene expression." in: Molecular and cellular biochemistry, Vol. 305, Issue 1-2, pp. 35-44, (2007) (PubMed).

  • 抗原

    SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

    别名

    SETDB1

    背景

    This gene encodes a histone methyltransferase. The encoded enzyme catalyzes the reaction of S-adenosyl-Lmethionine and histone L-lysine to produce S-adenosyl-L-homocysteine and histone N(6)-methyl-L-lysine. The encoded protein likely functions in transcriptional repression.
    Tissue specificity: Widely expressed. High expression in testis.
    Synonyms: ESET, KG1T, KMT1E, KIAA0067, H3-K9-HMTase4, SETDB1

    分子量

    180kDa

    基因ID

    9869
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