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OGG1 抗体 (C-Term)

Cited in 5+ publications. This 兔 多克隆 anti-OGG1 antibody specifically detects OGG1 in IHC. The antibody is reactive with 人 samples.
产品编号 ABIN966715
发货至: 中国
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Quick Overview for OGG1 抗体 (C-Term) (ABIN966715)

抗原

See all OGG1 抗体
OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

适用

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宿主

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克隆类型

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多克隆

标记

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This OGG1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
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    C-Term

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human OGG1 (N-glycosylase/DNA lyase)
  • 限制

    仅限研究用
  • 储存条件

    4 °C
  • Aburatani, Hippo, Ishida, Takashima, Matsuba, Kodama, Takao, Yasui, Yamamoto, Asano: "Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue." in: Cancer research, Vol. 57, Issue 11, pp. 2151-6, (1997) (PubMed).

    Rosenquist, Zharkov, Grollman: "Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 14, pp. 7429-34, (1997) (PubMed).

    Roldán-Arjona, Wei, Carter, Klungland, Anselmino, Wang, Augustus, Lindahl: "Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 15, pp. 8016-20, (1997) (PubMed).

    Kuo, Sklar: "Augmented expression of a human gene for 8-oxoguanine DNA glycosylase (MutM) in B lymphocytes of the dark zone in lymph node germinal centers." in: The Journal of experimental medicine, Vol. 186, Issue 9, pp. 1547-56, (1997) (PubMed).

    Bjorâs, Luna, Johnsen, Hoff, Haug, Rognes, Seeberg: "Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites." in: The EMBO journal, Vol. 16, Issue 20, pp. 6314-22, (1997) (PubMed).

  • 抗原

    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

    别名

    OGG1

    背景

    DNA repair enzyme that incises DNA at 8-oxoG residues. OGG1 (N-glycosylase/DNA lyase) excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-Nmethylformamidopyrimidine (FAPY) from damaged DNA. OGG1 has a beta-lyase activity that nicks DNA 3' to the lesion. Defects in OGG1 are associated with tumor formation.Defects in OGG1 are a cause of renal cell carcinoma OGG1 belongs to the type-1 OGG1 family.
    Synonyms: MMH, MUTM, OGH1

    途径

    DNA Damage Repair
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