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NOX3 抗体 (C-Term)

This anti-NOX3 antibody is a 兔 多克隆 antibody detecting NOX3 in IHC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN966688
发货至: 中国

Quick Overview for NOX3 抗体 (C-Term) (ABIN966688)

抗原

See all NOX3 抗体
NOX3 (NADPH Oxidase 3 (NOX3))

适用

人, 小鼠, 大鼠

宿主

  • 42

克隆类型

  • 42
多克隆

标记

  • 17
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NOX3 antibody is un-conjugated

应用范围

  • 33
  • 20
  • 13
  • 13
  • 9
  • 7
  • 3
  • 2
  • 2
  • 2
Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human NOX3(NADPH oxidase 3)
  • 限制

    仅限研究用
  • 储存条件

    4 °C
  • Ueno, Takeya, Miyano, Kikuchi, Sumimoto: "The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators." in: The Journal of biological chemistry, Vol. 280, Issue 24, pp. 23328-39, (2005) (PubMed).

    Cheng, Ritsick, Lambeth: "Nox3 regulation by NOXO1, p47phox, and p67phox." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34250-5, (2004) (PubMed).

    Cheng, Cao, Xu, van Meir, Lambeth: "Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5." in: Gene, Vol. 269, Issue 1-2, pp. 131-40, (2001) (PubMed).

  • 抗原

    NOX3 (NADPH Oxidase 3 (NOX3))

    别名

    NOX3

    背景

    NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. NOX3(NADPH oxidase 3) plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. NOX3(NADPH oxidase 3) is activated by the ototoxic drug cisplatin and by NOXO1. NOX3 is cooperatively activated by NCF1 and NCF2 or NOXA1 in a phorbol 12-myristate 13-acetate (PMA)-dependent manner. It is inhibited by diphenyleneiodonium chloride and interacts with and stabilizes CYBA/p22phox. NOX3 is expressed in fetal kidney and to a lower extent in liver, lung and spleen.
    Synonyms: MOX2
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