NOX3 抗体 (AA 287-336)
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北京 101111
Quick Overview for NOX3 抗体 (AA 287-336) (ABIN1535076)
抗原
See all NOX3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 287-336
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原理
- Nox3 Antibody
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特异性
- Nox3 Polyclonal Antibody detects endogenous levels of Nox3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human NOX3. AA range:287-336
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of D-galactose-induced aging rats." in: Hearing research, Vol. 287, Issue 1-2, pp. 15-24, (2012) (PubMed).
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- NOX3 (NADPH Oxidase 3 (NOX3))
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别名
- NOX3
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背景
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Synonyms: NOX3, MOX2, NADPH oxidase 3, Mitogenic oxidase 2, MOX-2, gp91phox homolog 3, GP91-3
Background: This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation.The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009],
Gene Name: NOX3
Protein Name: NADPH oxidase 3
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分子量
- 64 kDa
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基因ID
- 50508
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OMIM
- 607105
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UniProt
- Q9HBY0
抗原
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