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c-MYC 抗体

MYC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7E10 unconjugated
产品编号 ABIN966613
发货至: 中国
  • 抗原 See all c-MYC (MYC) 抗体
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This c-MYC antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human MYC expressed in E. Coli.
    克隆位点
    7E10
    亚型
    IgG1
    Top Product
    Discover our top product MYC Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Willmott: "Re: Alcohol hand-rub in psychiatric units--a risk to patients?" in: Burns : journal of the International Society for Burn Injuries, Vol. 35, Issue 4, pp. 610, (2009) (PubMed).

  • 抗原
    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
    别名
    Myc Proto-Oncogene protein (MYC 产品)
    背景
    The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
    Synonyms: MRTL, c-Myc, bHLHe39
    分子量
    49kDa
    基因ID
    4609
    途径
    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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