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MAP4K4 抗体 (AA 400-500)

This 小鼠 单克隆 antibody specifically detects MAP4K4 in WB 和 ELISA. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN966520
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAP4K4 抗体 (AA 400-500) (ABIN966520)

抗原

See all MAP4K4 抗体
MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))

适用

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宿主

  • 60
  • 5
小鼠

克隆类型

  • 58
  • 7
单克隆

标记

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This MAP4K4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

3C7B5
  • 抗原表位

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    AA 400-500

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of MAP4K4 (aa400-500) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Poinat, De Arcangelis, Sookhareea, Zhu, Hedgecock, Labouesse, Georges-Labouesse: "A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans." in: Current biology : CB, Vol. 12, Issue 8, pp. 622-31, (2002) (PubMed).

    Becker, Huynh-Do, Holland, Pawson, Daniel, Skolnik: "Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation." in: Molecular and cellular biology, Vol. 20, Issue 5, pp. 1537-45, (2000) (PubMed).

    Lantinga van Leeuwen, Teske, van Garderen, Mol: "Growth hormone gene expression in normal lymph nodes and lymphomas of the dog." in: Anticancer research, Vol. 20, Issue 4, pp. 2371-6, (2000) (PubMed).

  • 抗原

    MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))

    别名

    MAP4K4

    背景

    MAP4K4: mitogen-activated protein kinase kinase kinase kinase 4. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Synonyms: HGK, NIK

    基因ID

    9448
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