MAP4K4 抗体 (N-Term)
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北京 101111
Quick Overview for MAP4K4 抗体 (N-Term) (ABIN2783612)
抗原
See all MAP4K4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- MAP4K4 Antibody - N-terminal region
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序列
- PFIRDQPNER QVRIQLKDHI DRTRKKRGEK DETEYEYSGS EEEEEEVPEQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against MAP4K4. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP4K4
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anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibody
MAP4K4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4A5 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 866-1104) antibodyMAP4K4 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 400-500) antibodyMAP4K4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4H9E7 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 287-336) antibodyMAP4K4 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 兔, Cow, Pig, Bat, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (Internal Region) antibodyMAP4K4 适用: 人, 小鼠, 大鼠 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) antibodyMAP4K4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB1895 unconjugated Recombinant Antibody
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 611-710) antibodyMAP4K4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (AA 550-600) antibodyMAP4K4 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (pSer629) antibodyMAP4K4 适用: 人 DB 宿主: 兔 Polyclonal RB12877 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4) (pSer801) antibodyMAP4K4 适用: 人 DB 宿主: 兔 Polyclonal RB11324 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49031-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
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别名
- MAP4K4
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背景
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Background Information: MAP4K4 is the serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. MAP4K4 appears to act upstream of the JUN N-terminal pathway.The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene Name: Mitogen-activated protein kinase kinase kinase kinase 4
Alternative Symbols: HGK, NIK, MEKKK4, FLH21957, HEL-S-31
Protein Name: Mitogen-activated protein kinase kinase kinase kinase 4
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分子量
- 142kDa
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基因ID
- 9448
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NCBI登录号
- NP_004825
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UniProt
- O95819
抗原
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